Liposomes containing glycocholate as potential oral insulin delivery systems: preparation, in vitro characterization, and improved protection against enzymatic degradation
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چکیده
منابع مشابه
Liposomes containing glycocholate as potential oral insulin delivery systems: preparation, in vitro characterization, and improved protection against enzymatic degradation
BACKGROUND Oral delivery of insulin is challenging and must overcome the barriers of gastric and enzymatic degradation as well as low permeation across the intestinal epithelium. The present study aimed to develop a liposomal delivery system containing glycocholate as an enzyme inhibitor and permeation enhancer for oral insulin delivery. METHODS Liposomes containing sodium glycocholate were p...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2011
ISSN: 1178-2013
DOI: 10.2147/ijn.s19917